Assessment of Dialysis Initiation by a Fuzzy Mathematics Equation

Summary

The purpose of this study is to evaluate the impact of the optimal and late initiation of dialysis on the mortality and quality of life in end-stage renal disease (ESRD) patients by the Dialysis Initiation based on Fuzzy mathematics Equation (DIFE), which is a novel equation for the assessment of timing of dialysis initiation established by Fuzzy mathematics.

Conditions

• Chronic Kidney Disease

Interventions

OTHER

optimal start time

patients will start hemodialysis when their DIFE reach 35, and can not wait if the DIFE decline to 30.

OTHER

late start time

patients will start hemodialysis when their DIFE less than 30

Sponsors & Collaborators

• Chinese PLA General Hospital

  collaborator OTHER

• Fudan University

  collaborator OTHER

• RenJi Hospital

  collaborator OTHER

• Beijing Friendship Hospital

  collaborator OTHER

• Huashan Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• First Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• Chinese Academy of Medical Sciences, Fuwai Hospital

  collaborator OTHER

• First Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• The Second Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• General hospital of benxi iron and steel co.

  collaborator UNKNOWN

• Dalian Municipal Central Hospital

  collaborator OTHER

• An Steel Group Hospital

  collaborator UNKNOWN

• The First Affiliated Hospital of the Fourth Military Medical University

  collaborator OTHER

• General Hospital of Mining Industry Group Fuxin

  collaborator UNKNOWN

• Affiliated Zhongshan Hospital of Dalian University

  collaborator OTHER

• Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

  collaborator OTHER

• General Hospital of Ningxia Medical University

  collaborator OTHER

• Lanzhou University Second Hospital

  collaborator OTHER

• First Affiliated Hospital of Xinjiang Medical University

  collaborator OTHER

• First Hospital of China Medical University

  collaborator OTHER

• Central Hospital Affiliated to Shenyang Medical Collage

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Henan Provincial People's Hospital

  collaborator OTHER

• Guangdong Provincial People's Hospital

  collaborator OTHER

• The First Affiliated Hospital of Dalian Medical University

  lead OTHER

Principal Investigators

• Hongli Lin, MD， PhD · The First Affiliated Hospital of Dalian Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-04-14

Primary Completion

2024-05-20

Completion

2024-05-20

Countries

• China

Study Locations