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In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

NCT03384108 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-02-25

No results posted yet for this study

Summary

This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

Conditions

  • Healthy

Interventions

OTHER

5-13C-Glutamine

Intravenous infusion of 5-13C-Glutamine

OTHER

Bone marrow aspiration

Bone marrow aspiration of bone marrow aspirate

Sponsors & Collaborators

Principal Investigators

  • Wilson Gonsalves, MD · Mayo Clinic

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-01
Primary Completion
2028-01-31
Completion
2028-01-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03384108 on ClinicalTrials.gov