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Choline Source, Gut Microbiota and Trimethylamine-N-oxide Response

NCT04255368 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2020-11-04

No results posted yet for this study

Summary

The purpose of this research is to determine the production of trimethylamine-N-oxide (TMAO) from different forms of choline and whether this response is modified by the gut microbiota composition.

Conditions

  • Metabolism

Interventions

OTHER

Water-soluble choline

600 mg choline as choline bitartrate

OTHER

Fat-soluble choline

600 mg choline as phosphatidylcholine

OTHER

No choline control

No choline

Sponsors & Collaborators

  • Utah State University

    lead OTHER

Principal Investigators

  • Clara E Cho, PhD · Utah State University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-09
Primary Completion
2018-06-16
Completion
2020-07-25

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04255368 on ClinicalTrials.gov