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The Surgical Prognosis Based Diagnostic Strategy for Eosinophilic Chronic Rhinosinusitis

NCT03374124 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2017-12-15

No results posted yet for this study

Summary

Previous studies have demonstrated that the eosinophilic inflammation of nasal mucosa is associated with the uncontrolled condition of chronic rhinosinusitis after surgery. However, the definition of the eosinophilic chronic rhinosinusitis is not very clear. Japanese researchers have designed a scoring system to diagnose eosinophilic chronic rhinosinusitis. In this study, the investigators hope to examine the practicability of this scoring system and have a better knowledge of eosinophilic chronic rhinosinusitis in china.The retrospective study was conducted in a tertiary hospital. Participants received functional endoscopic sinus surgery more than 1 years were called back for evaluation. A diagnosis cut off value of eosinophil count was determined by the surgery prognosis. Then different factors were compared between participants with eosinophilic CRS and those with non-eosinophilic CRS to establish the appropriated diagnosis approach for eosinophilic CRS.

Conditions

  • Sinusitis
  • Nasal Polyps

Interventions

DIAGNOSTIC_TEST

sinonasal outcome test-22

Evaluate the nasal mucosal inflammation condition and overall quality-of-life of CRS patients

Sponsors & Collaborators

  • Jianbo Shi

    lead OTHER

Principal Investigators

  • Jianbo Shi, doctor · Ent department, the first affiliated hospital, Sun Yat-sen University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-01-31
Primary Completion
2018-01-31
Completion
2018-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03374124 on ClinicalTrials.gov