Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise Performance
NCT03350282 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2018-05-04
Summary
Co-administration of creatine and guanidinoacetic acid (GAA) has been recently put forward as an advanced dietary strategy to optimize tissue bioenergetics. The investigators hypothesized that creatine-GAA mixture would result in more powerful rise in brain and skeletal muscle creatine, as compared to creatine supplementation alone.
Conditions
- Energy Metabolism
Interventions
- DIETARY_SUPPLEMENT
-
GAA-creatine
- DIETARY_SUPPLEMENT
-
Creatine
Sponsors & Collaborators
-
University of Novi Sad, Faculty of Sport and Physical Education
lead OTHER
Principal Investigators
-
Sergej Ostojic, MD, PhD · University of Novi Sad
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-12-01
- Primary Completion
- 2018-05-01
- Completion
- 2018-05-01
More Related Trials
-
Creatine Kinetics, Synthesis From Glycine and Response to Creatine and Amino Acid Supplement in Healthy Humans
NCT01725503 ·Status: COMPLETED ·Phase: NA
-
Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males
NCT02094781 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of Different Forms of Creatine
NCT03039829 ·Status: COMPLETED ·Phase: NA
-
Creatine Effect on Brown Adipose Tissue Activation
NCT04086381 ·Status: COMPLETED ·Phase: NA
-
Creatine and Motor Skill Acquisition
NCT05201651 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
NCT07225335 ·Status: COMPLETED ·Phase: NA
-
Creatine Supplementation in Young Healthy Adults
NCT06604793 ·Status: RECRUITING ·Phase: NA
-
Creatine HCl Supplementation in Sarcopenia: A Randomized Controlled Study
NCT07285226 ·Status: RECRUITING ·Phase: NA
-
Effect of Creatine and Caffeine on Muscle Performance
NCT04290819 ·Status: UNKNOWN ·Phase: NA
-
Interval Training Plus Creatine Effects on Performance and Glucose Tolerance
NCT02370212 ·Status: COMPLETED ·Phase: NA
-
Gastrointestinal and Fluid Retention Symptoms Associated With Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation
NCT07176325 ·Status: COMPLETED
-
Essential Amino Acids and Protein Kinetics During Caloric Deprivation
NCT03372928 ·Status: COMPLETED ·Phase: NA
-
The Effects of Nutritional Supplementation on Occupational Performance in Firefighters
NCT06172543 ·Status: COMPLETED ·Phase: NA
-
β-alanine Supplementation on Knee Extensor Contractile and Force Properties
NCT02819505 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Betaine Supplementation on Strength and Muscle Creatine Content
NCT01213719 ·Status: COMPLETED ·Phase: NA
-
Effects of Resistance-band Training and Creatine and Whey Protein
NCT06606717 ·Status: RECRUITING ·Phase: NA
-
Creatine Supplementation During Resistance Training for People Recovering From Stroke
NCT03941678 ·Status: COMPLETED ·Phase: NA
-
Impact of Carbohydrate Co-ingestion on the Post-prandial Anabolic Response of Protein in Young and Elderly Men
NCT01576848 ·Status: COMPLETED ·Phase: NA
-
Impact of Amino Acids to Enhance Anabolism After Home-based Exercise
NCT04850820 ·Status: COMPLETED ·Phase: NA
-
Creatine Timing and Resistance Training Adaptations.
NCT03678857 ·Status: COMPLETED ·Phase: NA
-
Creatine Supplementation for Female Football
NCT06250556 ·Status: RECRUITING ·Phase: NA
-
Effect of Creatine Supplementation on Physical Performance in Vegan Subjects
NCT06483321 ·Status: COMPLETED ·Phase: NA
-
High Intensity Interval Training, Creatine Intake and Anaerobic Power
NCT05981820 ·Status: COMPLETED ·Phase: NA
-
Effects of Essential Amino Acid-enriched Whey and Carbohydrate Co-ingestion on Protein Kinetics
NCT04621175 ·Status: COMPLETED ·Phase: NA
-
Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults
NCT06606704 ·Status: RECRUITING ·Phase: NA