Prevalence of Antimicrobial-resistant Pathogens in Patients Admitted for UTIs
NCT03346603 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 801
Last updated 2021-07-08
Summary
Between 2013-2014, our study network of U.S. emergency departments, EMERGEncy ID NET, found that the rate of fluoroquinolone-resistant E. coli was 11.7% among all patients, 6.3% in uncomplicated and 19.9% in complicated. ESBL-producing Enterobacteriaceae were found in 7.7% of all cases, 2.6% in uncomplicated and 12.2% in complicated. More recently, Enterobactericeae and gram-negative non fermenting bacteria have started to show resistance to carbapenems (CREs and CR-NF). Patients hospitalized with UTI and urosepsis represent a higher risk population for infections due to multi-drug resistant bacteria and experience serious adverse outcomes, including death. EMERGEncy ID NET will conduct a study to determine the prevalence of ESBL-producing, CREs and CR-NFs among this high risk population of patients admitted for UTI from U.S. emergency departments.
Conditions
- Urinary Tract Infections
- Urosepsis
Interventions
- OTHER
-
urine culture and susceptibility testing
All patients will have a urine culture and susceptibility test ordered per standard care. Results of tests will identify which patients have antimicrobial-resistant organisms.
Sponsors & Collaborators
-
Centers for Disease Control and Prevention
collaborator FED -
IHMA laboratories
collaborator UNKNOWN -
Olive View-UCLA Education & Research Institute
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-02-08
- Primary Completion
- 2019-02-28
- Completion
- 2020-12-31
Countries
- United States
Study Locations
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