The Effect of Spironolactone on Acute Kidney Injury in Patients Undergoing Coronary Angiography

Summary

an interventional study to measure the possible effects of spironolactone ( an aldosterone antagonist) on the incidence of acute kidney injury after coronary angiography

Conditions

• Acute Kidney Injury
• IHD
• Contrast-induced Nephropathy

Interventions

DRUG

Spironolactone

each patient will receive 200 mg of spironolactone as per his/her angiography premedications

DRUG

Placebo Oral Tablet

Each patient will receive a placebo tablet as per his/her angiography premedications

Sponsors & Collaborators

• Ministry of Health-Basra Health Directorate-Al-Sader Teaching Hospital

  collaborator UNKNOWN

• Alhasan Mujtaba Abdul-Wahid

  lead OTHER

Principal Investigators

• Alhasan Mujtaba, BCPS · Baghdad University/College of Pharmacy/Department of Clinical Pharmacy

• Mohammed A Taher, Ph.D. · Baghdad University/College of Pharmacy/Department of Biochemistry

• Mazin A Hazzaa', Ph.D. · Al-Sader teaching Hospital/Basra Cardiac Center/M.D. Cardiologist

• Hassan M Al Rubaye, Ph.D · Al-Sader teaching Hospital/Basra Cardiac Center/M.D. Cardiologist

• Assad H Kata, Ph.D · Al-Sader teaching Hospital/Basra Cardiac Center/M.D. Cardiologist

• Hayder K Abdullkreem, M.Sc · Head of the clinical laboratory department/ Al-Sader teaching hopital

• Hamid A Abdulsada, Ph.D · Al-Sader teaching Hospital/Basra Cardiac Center/M.D. Cardiologist

• Abdul Ameer A Abdul Hameed, PH.D · Al-Sader teaching Hospital/Basra Cardiac Center/M.D. Cardiologist

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-09-01

Primary Completion

2018-09-01

Completion

2018-09-04

Countries

• Iraq

Study Locations