rTMS Posterior Parietal Cortex Modulation and Upper Limb Movement After Stroke

NCT03323255 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1

Last updated 2026-05-15

No results posted yet for this study

Summary

This study evaluates the effect of a unique session of inhibitory rTMS (cTBS) over the contralesional posterio parietal cortex (PPC) on the spatio-temporal parameters of a pointing movement performed by stroke patients with their paretic upper limb. It will also assess the effects on the resting motor threshold of both hemispheres and on parietopremotor connectivity.

To achieve theses aims, the real cTBS stimulation will be randomly counterbalanced with a SHAM stimulation (in a second session) in a crossover design. Assessments will be performed before and after each stimulation session.

Conditions

  • Stroke
  • Hemiparesis
  • Transcranial Magnetic Stimulation
  • Brain Connectivity

Interventions

DEVICE

repeated transcranial magnetic stimulation continuous theta-burst stimulation

cTBS

DEVICE

SHAM repeated transcranial magnetic stimulation

SHAM stimulation

Sponsors & Collaborators

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Etienne Allart, MD · University Hospital, Lille

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-10
Primary Completion
2021-08-01
Completion
2021-08-01

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03323255 on ClinicalTrials.gov