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Sympathetic-parasympathetic Ratio of Our Gaze

NCT03322904 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2017-10-26

No results posted yet for this study

Summary

ABSTRACT BACKGROUND The existence of the retinohypothalamic pathway suggests that light may influence autonomic outflow activity. The objective of this study was to examine the correlation between the estimated iris muscle sympathetic-parasympathetic area (IRIS) ratio and the sympathetic-parasympathetic ratio (low frequency \[LF\]/high frequency \[HF\] ratio).

METHODS The study population consisted of 200 females and 200 males (mean age, 32.4 ± 7.1 years). The IRIS ratio was determined from digital photographs of the iris in a computer setting. The LF/HF ratio was determined from records of heart rate variability obtained using a Holter implementation.

Conditions

  • Autonomic Nervous System Diseases

Interventions

DIAGNOSTIC_TEST

iris photography

The LF (0.04-0.15 Hz) and HF (0.16-0.4 Hz) ratings were recorded for 24 hours (day and night average) by Holter recording system Photographs of both irises of the healthy volunteers were taken . An image software program was used to draw circular limits over the iris exterior circle (IEC), coloretta circle (CC), and pupil circle (PC) on digital photographs. The areas between the circles were measured. The likelihood that the IRIS ratio was equal to the LF/HF ratio was calculated using the formula \[IEC-PC¬\] - \[CC-PC\] / \[CC-PC\].

Sponsors & Collaborators

  • Kecioren Education and Training Hospital

    lead OTHER

Principal Investigators

  • Zuhal Koç, specialist · Saglik Bilimleri Universitesi

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-10
Primary Completion
2017-03-05
Completion
2017-03-05

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03322904 on ClinicalTrials.gov