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The Effects of Mood on Cerebral Perfusion

NCT03302130 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2022-11-14

No results posted yet for this study

Summary

Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the effects of a different mood state (neutral, positive and negative mood), induced using subjects own memories, on both global and regional cerebral perfusion, measured with arterial spin labeling.

Conditions

  • Cerebral Perfusion

Interventions

BEHAVIORAL

Mood induction (using own memories)

Subjects deliver three positive, three negative and three neutral memories 30 seconds reliving a memory - answering questions about the memory - reliving memory for 2 minutes during ASL-MRI

DEVICE

Arterial spin labeling MRI

Single PLD PCASL

DEVICE

Physiological monitoring

During MRI: heart rate, end-tidal CO2, respiratory rate and skin conductance

Sponsors & Collaborators

  • University Ghent

    lead OTHER

Principal Investigators

  • Eric Achten, MD, PhD · University Hospital, Ghent

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-08
Primary Completion
2017-10-30
Completion
2017-11-17

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03302130 on ClinicalTrials.gov