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Diagnostic and Therapeutic Approaches to Hyperinflation and Small Airway Disease in COPD

NCT03287921 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26

Last updated 2020-03-31

No results posted yet for this study

Summary

Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. Hyperinflation and affection of the small airways are two components that are not represented in current diagnostic concepts and may relate to early stages of the disease. Moreover, optimal therapeutic interventions in patients with these distinct features remain unclear. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and initiating therapeutic strategies in early stage COPD within the GOLD recommendations.

Conditions

Interventions

DRUG

mono bronchodilatation

within indication according to current GOLD recommendation

DRUG

dual bronchodilatation

within indication according to current GOLD recommendation

Sponsors & Collaborators

  • Universitätsmedizin Mannheim

    lead OTHER

Principal Investigators

  • Frederik Trinkmann, MD · University Medical Center Mannheim

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-02
Primary Completion
2018-11-30
Completion
2019-04-11
FDA Drug
Yes

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03287921 on ClinicalTrials.gov