Maternal Autoimmune Disease Research Alliance (MADRA) Registry
NCT03276923 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2026-01-08
Summary
This multi-site registry, centered at Duke University, will enroll pregnant women with autoimmune and rheumatologic diseases.
The main goal of MADRA is to identify ways to improve the health of women with rheumatic diseases and their babies during pregnancy.
Prior studies demonstrate the importance of increase inflammation prior to and during pregnancy on these outcomes. The future research will seek to better define these risk factors and to identify ways to may improve them.
Conditions
- Autoimmune Diseases
- Pregnancy Related
- Systemic Lupus Erythematosus
- Cutaneous Lupus
- Rheumatoid Arthritis
- Sjogren's Syndrome
- Scleroderma
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Megan EB Clowse, MD, MPH · Duke Health
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-01-01
- Primary Completion
- 2027-01-01
- Completion
- 2027-01-01
Countries
- United States
Study Locations
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