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Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments

NCT01642706 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2020-07-21

No results posted yet for this study

Summary

B cells are known to play an important role in auto-immune diseases by activating T cells, secreting inflammatory cytokines and autoreactive antibodies. However, a sub-type of B cells named regulatory B cells or Bregs has recently shown capacities to prevent or cure arthritis in mouse models. Bregs have also been identified in humans.

Conditions

Sponsors & Collaborators

  • University Hospital, Montpellier

    lead OTHER

Principal Investigators

  • Jacques Morel, MD, PhD · University Hospital, Montpellier

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-07-02
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01642706 on ClinicalTrials.gov