A Study of Exosome Proteomics and Hemodynamics in Sepsis
NCT03267160 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2021-02-10
Summary
This research will be the first study for exosomes purified in blood and urine from septic patients who had multiple organ failures. Proteomics studies in exosomes from blood or urine specimens. Analyze autophage, and apoptosis related biomarkers of exosomes by bioinformatics. To find the correlations between exosomes biomarkers and hemodynamic parameters.
Conditions
- Hemodynamic Instability
- Autophagy
Interventions
- DIAGNOSTIC_TEST
-
Hemodynamic parameters
Pulse contour cardiac output monitored heart contractility, end-diastolic volume parameters, and lung water parameters.
Sponsors & Collaborators
-
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
lead OTHER
Principal Investigators
-
Wen-Lin Su, PhD · Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital
Eligibility
- Min Age
- 20 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-18
- Primary Completion
- 2020-01-30
- Completion
- 2020-01-30
Countries
- Taiwan
Study Locations
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