A Study of Exosome Proteomics and Hemodynamics in Sepsis

NCT03267160 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2021-02-10

No results posted yet for this study

Summary

This research will be the first study for exosomes purified in blood and urine from septic patients who had multiple organ failures. Proteomics studies in exosomes from blood or urine specimens. Analyze autophage, and apoptosis related biomarkers of exosomes by bioinformatics. To find the correlations between exosomes biomarkers and hemodynamic parameters.

Conditions

  • Hemodynamic Instability
  • Autophagy

Interventions

DIAGNOSTIC_TEST

Hemodynamic parameters

Pulse contour cardiac output monitored heart contractility, end-diastolic volume parameters, and lung water parameters.

Sponsors & Collaborators

  • Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

    lead OTHER

Principal Investigators

  • Wen-Lin Su, PhD · Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital

Eligibility

Min Age
20 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-18
Primary Completion
2020-01-30
Completion
2020-01-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03267160 on ClinicalTrials.gov