Serum iPTH, Calcium and Phosphate, and the Risk of Mortality in Beijing Elderly Hemodialysis Population
NCT03261154 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2017-08-24
Summary
Incidence of End Stage Renal Disease (ESRD) amongst elderly patient group is continuously increasing with population aging progressing. Mineral and bone disorder (MBD) is a common complication caused by ESRD, it raises the incidence of cardiovascular disease (CVD) in hemodialysis patients, as well as mortality.
Joint effects of Kidney failure and aging on elderly hemodialysis patients make the contribution factors of CKD-MBD quite complex, and it also leads to differences in clinic manifestation between elderly hemodialysis patients and non-elderly hemodialysis patients. Since not much studies had been done for this specific subject, thus, research on elderly patients who is taking Maintenance hemodialysis is very necessary. This study is a retrospective research to identify optimized target value of Calcium and Phosphorus for elderly patients taking maintenance hemodialysis and hence provide guidance for clinical practices. The data for this study will be provided by Beijing Blood Purification Quality Control and Improvement Center. Clinical files and Calcium and Phosphorus metabolic indices will be collected amongst elderly patients who were elder than 65 years and was taking maintenance hemodialysis between Jan 1st, 2012 through Dec 31st, 2016. Relationship between Calcium level, Phosphorus level, iPTH index, all-cause mortality and CVD caused mortality will be analyzed to identify optimized range of target Calcium levels, Phosphorus level for hemodialysis treatment
Conditions
Sponsors & Collaborators
-
Wenhu Liu
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-01-01
- Primary Completion
- 2016-12-31
- Completion
- 2016-12-31
Countries
- China
Study Locations
More Related Trials
-
The Effect of Etelcalcetide on CKD-MBD
NCT03960437 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of Different Dialysate Calcium Concentration
NCT01839383 ·Status: UNKNOWN ·Phase: NA
-
the Study on Prognostic for Hemodialysis Patients
NCT03194087 ·Status: UNKNOWN
-
Mineral and Bone Disorders Outcomes in Stage 5D of Chronic Kidney Disease
NCT00995163 ·Status: COMPLETED
-
The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKD
NCT06398002 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
NCT03427944 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Phosphorus on Valvular and Vascular Calcification in ESRD
NCT03360331 ·Status: UNKNOWN
-
The Efficacy and Safety of Microwave Ablation for Mild-to-moderate Secondary Hyperparathyroidism Patients Undergoing Hemodialysis
NCT02332135 ·Status: UNKNOWN ·Phase: NA
-
Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease Patients
NCT02999204 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Different Continuous Renal Replacement Therapy Patterns on Ionized Calcium in Patients With Citrate Anticoagulants Using Calcium-containing Replacement Solutions
NCT06021080 ·Status: RECRUITING
-
Cincalcet and Vascular Arterial Stiffness Among Peritoneal Dialysis Patients With Secondary Hyperparathyroidism
NCT01143987 ·Status: COMPLETED ·Phase: PHASE4
-
Serum Magnesium and Vascular Calcification
NCT01293786 ·Status: COMPLETED
-
Biomarkers and Event Patterns of Vascular Disease in Hemodialysis
NCT07170761 ·Status: ACTIVE_NOT_RECRUITING
-
FGF-23 and PTH in Hemodialysis Patients
NCT04350944 ·Status: COMPLETED
-
Sevelamer, FGF-23 and Endothelial Dysfunction in Chronic Kidney Disease (CKD)
NCT01135615 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Patients
NCT02498457 ·Status: UNKNOWN ·Phase: NA
-
Kidney Yin/Yang Replenishment on Patients With Renal Osteodystrophy
NCT01665651 ·Status: WITHDRAWN ·Phase: PHASE2
-
Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol
NCT01725113 ·Status: TERMINATED ·Phase: PHASE4
-
Study of Individualized Therapy on Hyperphosphatemia in Maintenance Hemodialysis Patients
NCT02684643 ·Status: COMPLETED ·Phase: NA
-
The Efficacy of Niacin on Hyperphosphatemia in Patients Undergoing Haemodialysis
NCT03163576 ·Status: UNKNOWN ·Phase: PHASE4
-
The Influence of Low Phosphorus in Hemodialysis Patients
NCT04645459 ·Status: UNKNOWN ·Phase: NA
-
Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure
NCT00124969 ·Status: COMPLETED ·Phase: PHASE4
-
Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients
NCT05720273 ·Status: RECRUITING ·Phase: PHASE4
-
Alendronate for Vascular Calcification in Peritoneal Dialysis Patients?
NCT00299572 ·Status: UNKNOWN ·Phase: PHASE4
-
Keto-/Amino Acid Supplemented Low Protein Diet in Patients With Chronic Kidney Disease
NCT00364884 ·Status: UNKNOWN ·Phase: PHASE4