Neurofilaments for NEDA Assessing in MS
NCT03250169 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 21
Last updated 2022-02-25
Summary
Goal is to evaluate the achievement of biological NEDA as demonstrated by a drop in neurofilament levels in MS patients commencing Alemtuzumab therapy as part of their MS management.
Conditions
Interventions
- DRUG
-
Alemtuzumab
Licensed dose
Sponsors & Collaborators
-
Queen Mary University of London
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-08-01
- Primary Completion
- 2022-01-28
- Completion
- 2022-01-28
- FDA Drug
- Yes
Countries
- United Kingdom
Study Locations
More Related Trials
-
Alemtuzumab on Surrogate Markers of Disease Activity and Repair Using Advanced MRI Measures in Subjects With Relapsing Remitting Multiple Sclerosis
NCT01395316 ·Status: COMPLETED ·Phase: PHASE4
-
Testing Mitochondria Activity and Blood Lipid Content of Multiple Sclerosis Patients
NCT01918501 ·Status: UNKNOWN ·Phase: NA
-
Advanced MRI Measures of Repair in Alemtuzumab Treated Patients
NCT01307332 ·Status: COMPLETED ·Phase: PHASE3
-
MicroRNA-150 and microRNA-155 in Multiple Sclerosis
NCT04300543 ·Status: UNKNOWN
-
To Study the Pathophysiological Features of Multiple Sclerosis
NCT04242056 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Monthly Monitoring of Plasma NfL in Treated Relapsing-remitting Multiple Sclerosis to Detect Persistent Infraclinical Disease Activity
NCT07292480 ·Status: RECRUITING ·Phase: NA
-
Aspirin for Treatment of Multiple Sclerosis-Related Fatigue
NCT00467584 ·Status: TERMINATED ·Phase: PHASE3
-
Observational Trial Evaluating Elevated Factor VIII Related Labs as a Biomarker for Incomplete Relapse Recovery
NCT05926167 ·Status: UNKNOWN
-
Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis
NCT03983252 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis
NCT05177523 ·Status: RECRUITING
-
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
NCT00001248 ·Status: RECRUITING
-
Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease
NCT07025122 ·Status: ENROLLING_BY_INVITATION
-
Single Test to ARrive at MS Diagnosis. Using a Single MRI Brain Scan to Help Diagnose Multiple Sclerosis
NCT02485223 ·Status: UNKNOWN
-
Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis
NCT00854750 ·Status: TERMINATED ·Phase: PHASE4
-
Analyze the Myelin-TRAP as Diagnostic Tool in Multiple Sclerosis
NCT01723631 ·Status: TERMINATED ·Phase: NA
-
Ocrelizumab or Alemtuzumab Compared With Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis - a Phase-2 Randomised Controlled Trial
NCT04971005 ·Status: TERMINATED ·Phase: PHASE2
-
Serum Neurofilament-light Chain and GFAP Levels in Patients From the OFSEP Cohort at Different Landmarks of Multiple Sclerosis
NCT03981003 ·Status: RECRUITING
-
Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
NCT04380220 ·Status: UNKNOWN
-
A Study of MSDx Complex 1 as a Marker for Therapy Response in Multiple Sclerosis
NCT01541618 ·Status: COMPLETED
-
Serum Neurofilament Light in Multiple Sclerosis
NCT06282081 ·Status: ACTIVE_NOT_RECRUITING
-
Advanced MRI Sequences in Multiple Sclerosis and Its Mimics
NCT03608605 ·Status: UNKNOWN
-
Relationship Between the Nutritional Habits and Relapsing and Disability Rates in Patient With Multiple Sclerosis.
NCT04110171 ·Status: UNKNOWN
-
A Study of Oxidative Pathways in MS Fatigue
NCT02804594 ·Status: COMPLETED ·Phase: PHASE2
-
Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis
NCT04053374 ·Status: UNKNOWN
-
A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
NCT05090371 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4