Hypofractionated Radiation Therapy for Glioblastoma
NCT03212235 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 58
Last updated 2017-07-11
Summary
Notwithstanding major improvements in treatment modalities, the prognosis of patients with glioblastoma is poor. Hypofractionated radiation therapy as an alternative of the standard 6-week regimen could be an attractive approach as an effort to prevent tumor cell repopulation and reduction the total treatment period promoting patient comfort and convenience.
Conditions
Interventions
- RADIATION
-
Hypofractionated radiation therapy
Hypofractionated radiation therapy Total dose: 60 Gy (20 fractions / 3 Gy per fraction)
Sponsors & Collaborators
-
Instituto do Cancer do Estado de São Paulo
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-06-05
- Primary Completion
- 2019-06-01
- Completion
- 2020-06-01
Countries
- Brazil
Study Locations
More Related Trials
-
Carbon Ion Radiotherapy for Primary Glioblastoma
NCT01165671 ·Status: COMPLETED ·Phase: NA
-
Simultaneous Integrated Boost FDOPA Positron Emission Tomography (PET) Guided in Patients With Partially- or Non-operated Glioblastoma
NCT05653622 ·Status: RECRUITING ·Phase: PHASE2
-
Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.
NCT03411408 ·Status: UNKNOWN ·Phase: NA
-
Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma
NCT00978458 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Radiosurgery for Glioblastoma Multiforme
NCT00456612 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00099125 ·Status: COMPLETED ·Phase: PHASE2
-
Low Dose Radiation Therapy for Glioblastoma Multiforme
NCT01466686 ·Status: COMPLETED ·Phase: PHASE2
-
Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma
NCT03251027 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Glioblastoma Multiforme
NCT00820963 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform
NCT01120639 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
NCT00006916 ·Status: TERMINATED ·Phase: PHASE2
-
Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma
NCT00841555 ·Status: COMPLETED ·Phase: PHASE1
-
Glioblastoma Radiotherapy Using IMRT or Proton Beams
NCT04752280 ·Status: RECRUITING ·Phase: NA
-
Dose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of Glioblastomas in Adults
NCT01043536 ·Status: COMPLETED ·Phase: PHASE1
-
Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery
NCT04316039 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Surgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00053183 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Boost for Newly Diagnosed Glioblastoma Multiforme
NCT00376103 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF)
NCT06140875 ·Status: RECRUITING ·Phase: NA
-
Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma
NCT00003916 ·Status: COMPLETED ·Phase: PHASE3
-
Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT)
NCT01854554 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00482677 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00006353 ·Status: COMPLETED ·Phase: PHASE3
-
Phase I Dose Escalation in Patients With 1-3 Unresectable Brain Metastases
NCT02080949 ·Status: WITHDRAWN ·Phase: PHASE1
-
Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial
NCT06835803 ·Status: RECRUITING ·Phase: PHASE2
-
Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
NCT00305864 ·Status: COMPLETED ·Phase: PHASE1/PHASE2