Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma
NCT00003916 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2012-09-24
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells and may be an effective treatment for patients with glioma. Stereotactic radiation therapy may be able to deliver x-rays directly to the tumor and cause less damage to normal tissue. It is not yet known if standard radiation therapy is more effective when followed by stereotactic radiation therapy.
PURPOSE: Randomized phase III trial to compare the effectiveness of standard radiation therapy with or without stereotactic radiation therapy in treating patients who have glioma.
Conditions
Interventions
- RADIATION
-
radiation therapy
- RADIATION
-
stereotactic radiosurgery
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Brigitta Baumert, MD, PhD · UniversitaetsSpital Zuerich
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-04-30
- Primary Completion
- 2001-12-31
Countries
- Australia
- France
- Germany
- Netherlands
- Spain
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
NCT00377156 ·Status: COMPLETED ·Phase: PHASE3
-
Radiotherapy for Malignant Astrocytomas in the Elderly
NCT00430911 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
NCT00006916 ·Status: TERMINATED ·Phase: PHASE2
-
Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma
NCT00003375 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme
NCT00002545 ·Status: COMPLETED ·Phase: PHASE3
-
Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma
NCT03251027 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation.
NCT05102747 ·Status: RECRUITING ·Phase: NA
-
Radiation Therapy or Temozolomide in Treating Patients With Gliomas
NCT00182819 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas
NCT03956706 ·Status: WITHDRAWN ·Phase: NA
-
Radiation Therapy in Treating Young Patients With Gliomas
NCT00238264 ·Status: COMPLETED ·Phase: PHASE2
-
Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
NCT01372774 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00006353 ·Status: COMPLETED ·Phase: PHASE3
-
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
NCT01378481 ·Status: TERMINATED ·Phase: PHASE1
-
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
NCT00002708 ·Status: COMPLETED ·Phase: PHASE3
-
Adjuvant Stereotactic Fractionated Radiotherapy to the Resection Cavity in Recurrent Glioblastoma
NCT02715297 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiation Therapy in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Grade II or Grade III Meningioma
NCT00626730 ·Status: UNKNOWN ·Phase: PHASE2
-
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases
NCT00950001 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial
NCT03082846 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases
NCT01644591 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases
NCT00003911 ·Status: TERMINATED ·Phase: PHASE2
-
Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
NCT00305864 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
NCT01464177 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas
NCT00005602 ·Status: COMPLETED ·Phase: PHASE1
-
Stereotactic Radiation Therapy Before Surgery for the Treatment of Resectable Brain Metastases
NCT04069910 ·Status: WITHDRAWN ·Phase: NA
-
Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00482677 ·Status: COMPLETED ·Phase: PHASE3