Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
NCT03207854 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 625
Last updated 2026-04-02
Summary
This research trial collects and stores blood, tissue, and bone marrow specimens from patients with cancer or blood disorders, and healthy volunteers to study the immune system in a variety of different types of experiments, as well as associated clinical data as appropriate, focused on understanding mechanisms of immunotherapy.
Conditions
- Healthy Subject
- Hematologic and Lymphocytic Disorder
- Hematopoietic and Lymphoid Cell Neoplasm
- Immune System Disorder
- Malignant Neoplasm
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of peripheral blood, bone marrow, and tissue
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
- OTHER
-
Questionnaire Administration
Ancillary studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Southern California
lead OTHER
Principal Investigators
-
Casey O'Connell, MD · University of Southern California
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-04-12
- Primary Completion
- 2026-12-31
- Completion
- 2027-12-31
Countries
- United States
Study Locations
More Related Trials
-
Blood Sampling of Healthy Volunteers for Immunological Research
NCT03819829 ·Status: RECRUITING ·Phase: NA
-
In Vitro Studies of Immunological and Stem Cell Function in Peripheral Blood Mononuclear Cells in Patients
NCT00001336 ·Status: COMPLETED
-
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects
NCT04408950 ·Status: COMPLETED
-
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy People for the Expansion of T Cells for Adoptive Cell Therapy
NCT02821806 ·Status: RECRUITING
-
An Experimental Medicine Clinical Study to Compare Peripheral Immune System From Subjects Without Cancer Diagnosis and Patients With Solid Tumours.
NCT05133128 ·Status: TERMINATED ·Phase: NA
-
A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.
NCT00571389 ·Status: RECRUITING
-
Study of the Immune Response After Vaccination in Multiple Myeloma Patients
NCT02294487 ·Status: COMPLETED
-
PBMC Collection for Production of UCAR T Cells
NCT04963959 ·Status: UNKNOWN ·Phase: NA
-
Study of Blood Immune Cells in Cancer Patients Compared to Controls
NCT01312701 ·Status: UNKNOWN
-
Vaccine Therapy in Treating Patients With Refractory Stage IV Cancer
NCT00057915 ·Status: COMPLETED ·Phase: PHASE1
-
Immunity to Infection in Healthy Participants and Participants With Cancer
NCT05787964 ·Status: ACTIVE_NOT_RECRUITING
-
A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.
NCT05230186 ·Status: UNKNOWN
-
Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer
NCT00823524 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands
NCT02203825 ·Status: COMPLETED ·Phase: PHASE1
-
Prospective Study of White Blood Cells
NCT04838171 ·Status: RECRUITING
-
Evaluation of Immune Signaling Networks in Healthy Human Volunteers
NCT01882582 ·Status: COMPLETED
-
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
NCT04242095 ·Status: RECRUITING
-
Evaluation of Immunologic Response Following COVID-19 Vaccination in Children, Adolescents, and Young Adults With Cancer
NCT05228275 ·Status: ACTIVE_NOT_RECRUITING
-
Immune Cell Therapy for Advanced Solid Tumors
NCT07260058 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients
NCT04948619 ·Status: RECRUITING ·Phase: PHASE2
-
A Pilot Study of Tumor Cell Vaccine for High-risk Solid Tumor Patients Following Stem Cell Transplantation
NCT00405327 ·Status: COMPLETED ·Phase: PHASE2
-
Immunologic Response After Pandemic Influenza A (H1N1) Vaccine in Onco- Hematologic Patients
NCT01394640 ·Status: COMPLETED
-
Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy Recipients
NCT05164016 ·Status: COMPLETED
-
CD30 CAR for CD30+ NSGCT
NCT05634785 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Therapy in Treating Patients With Advanced Cancer
NCT00005956 ·Status: COMPLETED ·Phase: NA