Bacterial Infections in Cirrhotic Patients With Acute Severe Liver Injury
NCT03204591 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2018-06-06
Summary
Acute hepatic insults including hepatitis flare-up, active alcohol assumption and hepatotoxic drug use are common in patients with cirrhosis especially in Eastern countries.These patients are at high risk of developing acute-on-chronic liver failure (ACLF) and associated with high short-term mortality. And the natural history of these patients is frequently complicated by bacterial infections, which lead to deterioration of underlying diseases. The present study is aimed to investigate the prevalance and risk factors of bacterial infections in those patients and its impact on in-hospital/short-term mortality.
Conditions
- Cirrhosis, Liver
- Bacterial Infections
- Acute Liver Injury
Interventions
- OTHER
-
No intervention
No intervention
Sponsors & Collaborators
-
Ningbo No.2 Hospital
collaborator OTHER -
The Zhejiang Study Group for Organ Failure in Cirrhosis
lead OTHER
Principal Investigators
-
Jifang Sheng, Doctor · Department of infectious disease, First Affiliated Hospital of Zhejiang University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-07-20
- Primary Completion
- 2018-10-18
- Completion
- 2019-01-18
Countries
- China
Study Locations
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