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Pattern of Acute on Chronic Liver Failure in Patient With HCV Related Chronic Liver Disease

NCT03456518 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2020-01-23

No results posted yet for this study

Summary

The concept of acute-on-chronic liver failure (ACLF) was introduced by Jalan and Williams in 2002 to describe the acute deterioration in liver function over 2 to 4 weeks in a patient with well-compensated cirrhosis associated with a precipitating event (hepatotoxic: superimposed hepatitis viral infection, drug-induced liver injury, hepatotoxins, or excessive alcohol consumption; extra hepatic: variceal bleeding or sepsis), leading to severe deterioration in clinical status with jaundice and hepatic encephalopathy and/or HRS. Following this concept, several proposals for the diagnostic criteria of ACLF have been suggested.

Conditions

  • Acute-On-Chronic Liver Failure

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Mohammed Medhat · Al-Arajhy Liver Hospital, Assiut University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-11-01
Primary Completion
2019-10-31
Completion
2019-11-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03456518 on ClinicalTrials.gov