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Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression

NCT03202914 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 840

Last updated 2017-06-29

No results posted yet for this study

Summary

The present record represents a secondary data analysis of the Modification of Diet in Renal Disease (MDRD) Study. For this analysis, the MDRD study data and specimens were retrieved from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository. A global, untargeted, metabolomic profile was used to investigate biomarkers of dietary intake as well as biomarkers of kidney disease progression.

Conditions

  • Dietary Modification
  • Kidney Diseases, Chronic

Interventions

BEHAVIORAL

Usual protein and phosphorus diet

Diet intervention

BEHAVIORAL

Low protein and phosphorus diet

Diet intervention

BEHAVIORAL

Very low protein and phosphorus

Diet intervention

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • Tufts Medical Center

    collaborator OTHER

  • Johns Hopkins Bloomberg School of Public Health

    lead OTHER

Principal Investigators

  • Casey M. Rebholz, PhD, MPH, MS · Johns Hopkins Bloomberg School of Public Health

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1988-10-31
Primary Completion
1993-05-31
Completion
2016-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03202914 on ClinicalTrials.gov