Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia
NCT03197064 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 11
Last updated 2022-07-18
Summary
The purpose of this study is to determine if intravenous fosaprepitant can interfere with nervous system monitoring signals in patients having surgery under general anesthesia. This medication has numerous effects on the sensory nerve transmission which can theoretically have effects on the ability to accurately measure somatosensory evoked potentials.
Conditions
- Postoperative Nausea
Interventions
- DRUG
-
Fosaprepitant 150 mg
Antiemetic used to prevent nausea and vomiting after general anesthesia.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Mark A Burbridge, MD · Stanford University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-01-01
- Primary Completion
- 2020-01-31
- Completion
- 2020-01-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Characterizing Transcranial Focused Ultrasound Neuromodulation During Sedation
NCT07161518 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE4
-
Effects of Desflurane-propofol Balanced Anesthesia on Visual Evoked Potentials Monitoring
NCT05465330 ·Status: COMPLETED ·Phase: NA
-
Neural and Antidepressant Effects of Propofol
NCT03684447 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
General Anesthetic Mode and Postoperative Complications
NCT03335579 ·Status: TERMINATED
-
Relationship Between Pre-induction Electroencephalogram Pattern of Adult Patients and Their Sensitivity to Propofol
NCT04520503 ·Status: COMPLETED
-
Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Healthy Volunteers
NCT00321360 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Valproate on Propofol
NCT01170377 ·Status: COMPLETED
-
The Electroencephalogram Analysis in the Differences Between Inhalation Anesthetic and Propofol.
NCT04431557 ·Status: COMPLETED
-
Fospropofol Disodium ED95 for Elderly Spinal Anesthesia Sedation
NCT07333508 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
The Effect of Palonosetron on the QTc Interval During Perioperative Period
NCT01650961 ·Status: COMPLETED ·Phase: NA
-
Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia
NCT07092384 ·Status: COMPLETED ·Phase: NA
-
Exploring Self-regulatory Processes in Anesthesiologists During Massive Transfusion
NCT02199210 ·Status: UNKNOWN ·Phase: NA
-
The Effect of a Reduced Noise Environment on the Response Time of the Anesthesia Provider
NCT03507855 ·Status: COMPLETED ·Phase: NA
-
The Impact of Methylprednisolone Sodium Succinate on Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgery: A Target Trial Emulation Study
NCT07271394 ·Status: COMPLETED
-
Effect of Etomidate and Propofol on Electroencephalography
NCT04369014 ·Status: UNKNOWN ·Phase: NA
-
Propofol's Hypnotic and Memory Effects
NCT00576615 ·Status: COMPLETED
-
Neuronal Mechanisms of Sensory Processing During General Anesthesia
NCT00434382 ·Status: UNKNOWN ·Phase: NA
-
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
NCT01543633 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
NCT06573489 ·Status: RECRUITING ·Phase: PHASE4
-
Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia
NCT03528954 ·Status: COMPLETED ·Phase: NA
-
The Application of Target Controlled Infusion of Etomidate Combined With Propofol in the Maintenance of Anesthesia During Brain Surgeries
NCT02174120 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor
NCT02813044 ·Status: COMPLETED ·Phase: NA
-
EEG Analysis During Light Propofol Sedation
NCT03362775 ·Status: UNKNOWN ·Phase: PHASE1
-
Monitoring Exhaled Propofol to Individualize General Anesthesia
NCT01191021 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Propofol Requirement Between Patients With Pituitary Somatotroph Tumor and With Nonfunctioning Pituitary Tumor in Transsphenoidal Pituitary Surgery Under Total Intravenous Anesthesia
NCT03465423 ·Status: COMPLETED