iCAGES-guided Precision Therapy for Cancers in Contrast to Standard Care or IHC-guided Theray
NCT03192501 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250
Last updated 2024-06-25
Summary
This study prospectively evaluates whether the use of iCAGES (integrated CAncer GEnome Score) tool in guiding the treatment of advanced cancers is superior to current standard care or IHC-guided therapy in progress free survival (PFS),overall survival (OS),and improvement of life quality.
Conditions
- Lung Cancer
- Gene Abnormality
- Gene Product Sequence Variation
- Cancer
Interventions
- DRUG
-
inhibitors, ADC drugs such as tarceva, capmatinib, padcev et al for A/C group.
Choose appropriate targeted drugs according to NGS/IHC results.
Sponsors & Collaborators
-
The First Affiliated Hospital of Guangzhou Medical University
collaborator OTHER -
Sun Yat-sen University
collaborator OTHER -
Second Affiliated Hospital of Guangzhou Medical University
lead OTHER
Principal Investigators
-
Zhenfeng Zhang, MD,PhD · Second Affiliated Hospital of Guangzhou Medical University
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-07-01
- Primary Completion
- 2030-07-01
- Completion
- 2039-07-01
- FDA Drug
- Yes
Countries
- China
Study Locations
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