MedTrace Logo

Heart Failure Study of Multi-site Pacing Effects on Ventriculoarterial Coupling

NCT03189368 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2020-09-11

No results posted yet for this study

Summary

To perform a comparative study of multi-site left ventricular pacing and cardiac resynchronization therapy effects on ventriculoarterial coupling and energy efficiency of the failing heart

Conditions

Interventions

DEVICE

Activation of multi-site pacing capability on CRT devices

Instead of administering a single LV pulse at the most (electrically) delayed segment of the ventricle, multi-site pacing allows for a more detailed "sculpting" of the LV activation sequence. Based on the MPP-IDE study results, activation of the antero-lateral wall, or at least its most delayed segments, closely followed by a pulse to the apex and then by a right ventricular one will yield favorable results in terms of hemodynamics and clinical parameters. Programming features: * Interpolar distance for the first left ventricular pulse \>30mm (i.e. non-sequential poles used) * Nearly simultaneous (Δt=5msec) second left ventricular pulse and * Threshold of ≤[email protected]

Sponsors & Collaborators

  • National and Kapodistrian University of Athens

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-09-18
Primary Completion
2020-09-01
Completion
2020-09-01
FDA Device
Yes

Countries

  • Greece

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03189368 on ClinicalTrials.gov