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The Role of Stem Cells on Immune Cells in the Development of Cardiovascular Diseases

NCT03172507 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2019-04-01

No results posted yet for this study

Summary

An observational pilot proof-of-principle study. 15 patients with significant coronary artery disease and 15 matched controls. To investigate whether long-term activation of the innate immune system, named 'trained innate immunity', occurs at the level of the bone marrow progenitor cells in patients with significant coronary artery disease and whether this correlates with the proinflammatory phenotype of monocytes.

Conditions

Sponsors & Collaborators

  • Canisius-Wilhelmina Hospital

    collaborator OTHER

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Niels P. Riksen, MD, PhD · Radboud University Medical Center

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-20
Primary Completion
2018-08-31
Completion
2018-10-01

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03172507 on ClinicalTrials.gov