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Volatile Organic Compounds as Markers of Acute Rejection in Lung Transplant

NCT03172091 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2021-04-26

No results posted yet for this study

Summary

The aim of research is to identify markers of acute rejection by VOC analysis in exhaled breath of bilateral-lung transplanted patients. 120 bi-lung transplanted patients will be divided into two groups : patients with acute rejection diagnosed on transbronchial biopsies and patients with no acute rejection. Exhaled breath will be collected for VOC analysis woth electronic nose and mass spectrometry. VOC profiles will be compared between the two groups of patients.

Conditions

  • Transplant; Complication, Rejection

Interventions

DEVICE

eNose (electronic nose)

Collection of exhaled breath for an immediate analysis by electronic nose

DEVICE

Spectrometry

Collection of exhaled breath for an immediate analysis by mass spectrometry

Sponsors & Collaborators

  • Hopital Foch

    lead OTHER

Principal Investigators

  • Jean-Louis Couderc, MD-PhD · Pneumologie Hopital Foch

  • Antoine Roux · Pneumologie Hopital Foch

  • Hélène Salvator, MD · Pneumologie Hopital Foch

  • Philippe Devillier, MD-PhD · UPRES EA 220 Hopital Foch

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-27
Primary Completion
2021-10-31
Completion
2021-10-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03172091 on ClinicalTrials.gov