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Effects of Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Cytokines

NCT03164590 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2020-01-22

No results posted yet for this study

Summary

This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on inflammatory cytokine response after total abdominal hysterectomy.

Conditions

  • Endometrial Adenocarcinoma

Interventions

DRUG

Ketamine

patients receive local anesthetic wound infiltration with 1 mg /kg ketamine

DRUG

dexmedetomidine

patients receive local anesthetic wound infiltration with 1µg/kg dexmedetomidine

DRUG

bupivacaine

patients receive local anesthetic wound infiltration with bupivacaine 0.5 % diluted in 20 ml saline

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • fatma el sherif, MD · South Egypt Cancer Institute

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-06-01
Primary Completion
2018-08-01
Completion
2018-09-01
FDA Drug
Yes

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03164590 on ClinicalTrials.gov