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Pharmacokinetics of Paracetamol and Antiepileptic Drugs After Sleeve Gastrectomy

NCT03161509 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 2

Last updated 2021-09-24

No results posted yet for this study

Summary

Sleeve gastrectomy may affect drug pharmacokinetics in several potential ways. We will measure pharmakokinetics of paracetamol and antiepileptic drugs before and 6 months after sleeve gastrectomy.

Conditions

  • Bariatric Surgery Candidate

Interventions

DRUG

Paracetamol

single dose of 1 gr paracetamol

DRUG

Antiepileptic (either carbamazepine, lamotrigine, phenytoin or valproic acid)

Single dose of antiepileptic drug (either carbamazepine, lamotrigine, phenytoin or valproic acid) for which the participant is taking chronically in stable dose

Sponsors & Collaborators

  • Rambam Health Care Campus

    lead OTHER

Principal Investigators

  • Irit Hochberg, MD/PhD · Rambam Healthcare Campus

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-07-01
Primary Completion
2018-12-01
Completion
2019-01-01

Countries

  • Israel

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03161509 on ClinicalTrials.gov