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Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials

NCT03149172 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2020-09-25

Study results available
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Summary

The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using histomorphometric and micro CT analysis.The three xenograft materials under investigation are Bio-Oss® (bovine derived xenograft), Equimatrix® (equine derived xenograft), and Endobon® (bovine derived xenograft). There are no prospective studies comparing the effectiveness of these three materials, Bio-Oss®, Endobon® and Equimatrix®, when placed in extraction sockets.

Participants will be recruited from patients in the TUSDM clinics that require extraction of single rooted non-molar tooth and are treatment planned to receive dental implants in the future. Participants will be randomized to receive one of the three xenograft materials after tooth extraction. The percentage of newly formed bone and bone density will be compared between the three materials 4-6 months after ridge preservation.

Conditions

  • Alveolar Bone Loss

Interventions

DEVICE

Equimatrix®

Ridge preservation bone grafting after tooth extraction

DEVICE

Bio-Oss®

Ridge preservation bone grafting after tooth extraction

DEVICE

Endobon®

Ridge preservation bone grafting after tooth extraction

Sponsors & Collaborators

  • Tufts University

    lead OTHER

Principal Investigators

  • Yong Hur, DDS, DMD, MS · Tufts University School of Dental Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-20
Primary Completion
2016-06-07
Completion
2016-12-07
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03149172 on ClinicalTrials.gov