MedTrace Logo

Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study

NCT03147352 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 260

Last updated 2019-06-24

No results posted yet for this study

Summary

The investigators will analyze biomarkers related to the prognosis and treatment of necrotizing soft tissue infections (NSTI). The focus will be on whether certain endothelial and immune system biomarkers can function as markers of disease severity, mortality as well as the effects of hyperbaric oxygen therapy (HBOT). Biomarkers will be measured upon admission to an intensive care unit at Copenhagen University Hospital and during the following 3 days.

Conditions

  • Necrotizing Soft Tissue Infection
  • Necrotizing Fascitis
  • Gas Gangrene
  • Fournier Gangrene

Interventions

DEVICE

Hyperbaric oxygen therapy

Hyperbaric oxygen therapy with 100 % oxygen at 1.8 ATA for 2 hours.

Sponsors & Collaborators

  • Seventh Framework Programme

    collaborator OTHER

  • Ole Hyldegaard

    lead OTHER

Principal Investigators

  • Peter V Polzik, MD · Rigshospitalet, Denmark

  • Ole Hyldegaard, MD, PhD · Rigshospitalet, Denmark

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-02-28
Primary Completion
2018-01-31
Completion
2018-01-31

Countries

  • Denmark

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03147352 on ClinicalTrials.gov