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Combined Molecular and Mechanistic Methods for Detection of Pressure Ulcers

NCT06468306 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2024-06-21

No results posted yet for this study

Summary

This project aims to develop a novel method for identifying early tissue damage related to pressure ulcer (PU) development in vulnerable patients by measuring biomarkers of inflammation on the skin surface. PUs are common and costly injuries that result from prolonged pressure on the skin. Current methods to assess PU risk are unreliable, and the mechanisms of PU development are not well understood. This project contributes to new knowledge of PU etiology as well as the individual variability at a molecular level combined with new knowledge about nursing actions and clinical factors linked to PU progression and outcomes of prevention. The project will use non-invasive techniques and model-based analysis to identify specific biomolecules that reflect individual susceptibility to pressure exposure in different PU risk scenarios.

Conditions

  • Pressure Ulcer
  • Inflammatory Response

Interventions

PROCEDURE

non-invasive ventilation teraphy, NIV

Routine management regimes of NIV

Sponsors & Collaborators

  • Region Östergötland

    collaborator OTHER

  • Linkoeping University

    lead OTHER_GOV

Principal Investigators

  • Sara Bergstrand, PhD · Linkoeping University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-01
Primary Completion
2025-12-30
Completion
2027-12-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06468306 on ClinicalTrials.gov