Bacterial Transmission In Utero and IBD Risk
NCT03116568 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 180
Last updated 2023-02-08
Summary
Inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are caused by the loss of mucosal tolerance towards the commensal microbiota resulting in inflammatory responses.
Identifying intestinal bacteria in mother and newborn of both IBD and Control groups allow us to understand the change of bacterial composition human microbiome in the gut during pregnancy and childhood development.
Conditions
- IBD
- Pregnancy Related
- Microbiota
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Principal Investigators
-
Siew Chien Ng, PhD · Chinese University of Hong Kong
Eligibility
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-04-24
- Primary Completion
- 2025-04-14
- Completion
- 2027-09-27
Countries
- Hong Kong
Study Locations
More Related Trials
-
IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS IN INFLAMMATORY BOWEL DISEASE
NCT03809728 ·Status: RECRUITING ·Phase: NA
-
Early Inflammatory Bowel Disease Progression
NCT06756100 ·Status: RECRUITING
-
Biomarkers in Inflammatory Bowel Diseases
NCT02612103 ·Status: COMPLETED
-
Population Based Evaluation of the Use of TNFα Antagonists in Pregnant Women With Inflammatory Bowel Diseases
NCT03134508 ·Status: COMPLETED
-
Fertility and Pregnancy After Surgery IBD Audit
NCT04663971 ·Status: RECRUITING
-
The Effect of Intestinal Microbiota Transplantation for Inflammatory Bowel Diseases
NCT03426683 ·Status: COMPLETED ·Phase: NA
-
A Multicentered Prospective Cohort Study of Chinese IBD Patients
NCT05386290 ·Status: UNKNOWN
-
Serologic Markers for Inflammatory Bowel Disease During Clinical Forms With Weak or Strong Evolution Capacities
NCT01216514 ·Status: COMPLETED
-
Evaluation of Molecular Mechanisms of Non-response to Therapy in Patients With Inflammatory Bowel Disease
NCT05733845 ·Status: RECRUITING ·Phase: NA
-
Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
NCT06548399 ·Status: RECRUITING
-
Efficacy and Mechanism of Fecal Microbiota Transplantation of the Bai Ethnicity in the Treatment of UC
NCT06591013 ·Status: COMPLETED ·Phase: NA
-
Comparing the Accuracy of Different Ultrasound-based Scores to Assess Disease Severity in Patients with Inflammatory Bowel Disease
NCT06705972 ·Status: NOT_YET_RECRUITING
-
Assessing the Drug Exposure Risk of Infants Breastfed by Women With Inflammatory Bowel Disease
NCT03397108 ·Status: COMPLETED
-
Predictors of Prognosis in IBD Patients
NCT05653011 ·Status: RECRUITING
-
Predicting IBD Treatment Outcomes With Gut Microbiome Analysis
NCT06453720 ·Status: RECRUITING
-
Safety of IBD Drugs During Pregnancy and Breasfeeding: Mothers and Babies' Outcomes
NCT06337565 ·Status: RECRUITING
-
Impact of Obesity on Response to Therapy and Clinical Outcom in Patients With Inflammatory Bowel Disease
NCT07343726 ·Status: NOT_YET_RECRUITING
-
Microbiome and Genetic Analysis of Familial IBD
NCT03515070 ·Status: COMPLETED
-
Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD
NCT02197780 ·Status: COMPLETED
-
Standardized Fecal Microbiota Transplantation for Crohn's Diseases
NCT01793831 ·Status: RECRUITING ·Phase: NA
-
Epidemiology of IBD in Hong Kong: An Inception Cohort and Follow up Study
NCT02131168 ·Status: COMPLETED
-
Immune Function in Offsprings of Females With Inflammatory Bowel Disease
NCT02079441 ·Status: COMPLETED
-
Role of the Chemical Environment in the Pathogenesis of Inflammatory Bowel Disease
NCT03376230 ·Status: TERMINATED
-
Fecal Microbiota Transplantation for Ulcerative Colitis
NCT03016780 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients
NCT05967650 ·Status: UNKNOWN ·Phase: NA