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Circulating Extracellular Vesicles Released by Human Islets of Langerhans

NCT03106246 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2017-04-10

No results posted yet for this study

Summary

Beta-cells release extracellular vesicles (EV) and exosomes under normal and pathophysiologic conditions. These EV contain beta-cell specific autoantigens which may trigger the immune response at the initiation of type 1 diabetes. In this study, beta-cell derived EV will be detected and characterized in human blood samples.

Conditions

  • Type1 Diabetes Mellitus
  • Type2 Diabetes
  • Islet Cell Transplantation

Sponsors & Collaborators

  • CHU de Quebec-Universite Laval

    collaborator OTHER

  • McGill University Health Centre/Research Institute of the McGill University Health Centre

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-12-31
Primary Completion
2018-12-31
Completion
2019-07-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03106246 on ClinicalTrials.gov