Evaluation of the Efficacy of Intramuscular Islet Autograft After Extensive Pancreatectomy
NCT02872571 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2026-04-22
Summary
The liver may not be an optimal site for islet transplantation due to obstacles by an instant blood-mediated inflammatory response, and low revascularization of transplanted islets. Therefore, intramuscular islet transplantation offers an attractive alternative, based on its simplicity, enabling easier access for noninvasive graft imaging and cell explantation.
Conditions
- Disorder of Endocrine Pancreas
Interventions
- DRUG
-
Intramuscular Islet Autograft
Intramuscular Islet Autograft After Extensive Pancreatectomy
Sponsors & Collaborators
-
University Hospital, Lille
lead OTHER
Principal Investigators
-
François Pattou, MD, PhD · University Hospital, Lille
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-03-31
- Primary Completion
- 2026-04-30
- Completion
- 2026-04-30
Countries
- France
Study Locations
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