Platelet Function on Abacavir and Tenofovir
NCT03081572 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24
Last updated 2020-11-19
Summary
This is a small observational study aimed at observing differences in platelet function in HIV patients on abacavir versus tenofovir based anti-HIV drugs. There is some correlation between platelet activation and cardiovascular disease- this study will act as a pilot to see if platelet activation among abacavir users may explain the correlation between abacavir and cardiovascular disease in HIV positive patients.
This study will enroll 44 participants total; 22 on abacavir-based treatment, 22 on tenofovir-based treatment. There is only one study visit which includes a blood draw, physical assessment, and review of medical history.
Conditions
- Cardiovascular Diseases
- Platelet Aggregation, Spontaneous
- HIV/AIDS
Interventions
- DIAGNOSTIC_TEST
-
Platelet aggregation
Platelet aggregation
Sponsors & Collaborators
-
University of California, Los Angeles
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-04-30
- Primary Completion
- 2020-02-15
- Completion
- 2020-02-15
Countries
- United States
Study Locations
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