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The Role of the Nose in Snoring and Sleep Apnea

NCT03072173 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2017-03-07

No results posted yet for this study

Summary

We intend to study, in depth, the quantitative and qualitative properties of nasal respiration in sleep-disordered breathing and sleep apnea and its relation to (CPAP) treatment with the final goal of improving patient outcome.

To do this we will temporarily alter patients' nasal airflow during monitored sleep to lower CPAP air pressure, making CPAP treatment more acceptable to the patient. Additionally we plan to implement highly advanced computerized modelling in collaboration with the OSASMOD research consortium at St. Olavs Hospital/NTNU and SINTEF to predict the results of our alterations and ultimately, to use these predictions to improve both the planning and the outcomes of nasal surgery.

Conditions

  • Nasal Obstruction
  • Apnea, Obstructive Sleep

Interventions

DRUG

Xylometazoline

Patient will be given a nasal decongestant (Xylometazoline) prior to their 2nd or 3rd night of PSG.

DRUG

placebo (saline)

Patient will be given a placebo nasal spray (saline) prior to their 2nd or 3rd night of PSG.

Sponsors & Collaborators

  • Lovisenberg Diakonale Hospital

    lead OTHER

Principal Investigators

  • Søren Berg, MD PhD · University of Lund

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2018-06-30
Completion
2018-06-30

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03072173 on ClinicalTrials.gov