Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy
NCT03056885 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2017-02-17
Summary
This study evaluates the local cytokine inflammatory response during one lung ventilation in patients undergoing pulmonary lobectomy or wedge resection. We compare two different ventilation strategies: a conventional strategy with a protective strategy.
Conditions
- Ventilator-Induced Lung Injury
- Inflammatory Response
- Respiratory Complication
Interventions
- OTHER
-
Conventional One-Lung Ventilation
Vt 10 ml/kg
- OTHER
-
Protective One-lung ventilation
Vt 5 ml/kg
Sponsors & Collaborators
-
University of Roma La Sapienza
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-11-02
- Primary Completion
- 2015-11-25
- Completion
- 2016-01-15
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