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Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males

NCT03541395 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2018-05-30

No results posted yet for this study

Summary

The study is designed to identify and validate new protein biomarkers in blood related to testosterone activity. Thirty healthy young males underwent pharmaceutical castration to lower testosterone levels. After three weeks the subjects received an intramuscular injection of testosterone undecanoate. Blood samples from just before pharmaceutical castration, three weeks after castration, and one week after injection of testosterone undecanoate were collected representing normal testosterone levels, low testosterone levels, and testosterone at eugonadal levels.

Conditions

  • Hypogonadism, Male

Interventions

DRUG

GnRH antagonist

Sponsors & Collaborators

  • Lund University

    lead OTHER

Principal Investigators

  • Johan Malm, MD · Lund University

  • Roger Appelqvist, PhD · Lund University

  • Gyorgy Marko-Varga, PhD · Lund University

  • Aleksander Giwercman, MD · Lund University

  • Barbara Sahlin, MSc · Lund University

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2015-06-30
Completion
2015-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03541395 on ClinicalTrials.gov