Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With Paranasal Sinus or Nasopharyngeal Cancer
NCT03049358 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2019-02-05
Summary
This randomized phase I trial studies how well olfactory training works in improving sense of smell after radiation therapy in patients with paranasal sinus or nasopharyngeal cancer. Olfactory training may improve smell function after radiation therapy in patients with paranasal sinus or nasopharyngeal cancer.
Conditions
- Stage 0 Nasopharyngeal Carcinoma
- Stage 0 Paranasal Sinus Cancer
- Stage I Nasopharyngeal Carcinoma
- Stage I Paranasal Sinus Cancer
- Stage II Nasopharyngeal Carcinoma
- Stage II Paranasal Sinus Cancer
- Stage IIA Nasopharyngeal Carcinoma
- Stage IIB Nasopharyngeal Carcinoma
- Stage III Nasopharyngeal Carcinoma
- Stage III Paranasal Sinus Cancer
- Stage IV Nasopharyngeal Carcinoma
- Stage IV Paranasal Sinus Cancer
- Stage IVA Nasopharyngeal Carcinoma
- Stage IVA Paranasal Sinus Cancer
- Stage IVB Nasopharyngeal Carcinoma
- Stage IVB Paranasal Sinus Cancer
- Stage IVC Nasopharyngeal Carcinoma
- Stage IVC Paranasal Sinus Cancer
Interventions
- OTHER
-
Physiologic Testing
Undergo UPSIT smell test
- OTHER
-
Quality-of-Life Assessment
Ancillary studies
- PROCEDURE
-
Sham Intervention
Undergo sham training
- PROCEDURE
-
Therapeutic Procedure
Undergo olfactory training
- OTHER
-
rose essential oil
patient smells rose oil in vial
- OTHER
-
lemon essential oil
patient smells lemon oil in vial
- OTHER
-
clove essential oil
patient smells clove oil in vial
- OTHER
-
eucalyptus essential oil
patient smells eucalyptus oil in vial
- OTHER
-
canola oil placebo
patient smells canola oil in vial
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Zara Patel · Stanford University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-12-31
- Primary Completion
- 2018-10-31
- Completion
- 2018-10-31
Countries
- United States
Study Locations
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