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Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy

NCT07317752 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2026-01-05

No results posted yet for this study

Summary

The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy. It will also look at how these taste changes affect nutrition and quality of life. The main questions this study aims to answer are:

* How many participants develop changes in taste during chemotherapy?
* How do these changes affect eating habits, nutrition, and daily life?

Participants are women with non-metastatic breast cancer who are receiving chemotherapy before or after surgery.

Researchers will use standardized taste tests to measure how well participants can perceive different flavors. These tests are designed to provide accurate and reproducible results.

Participants will:

* Take part in taste tests during their chemotherapy treatment
* Have their nutritional status evaluated
* Answer questions about their quality of life

Conditions

  • Taste Disorders
  • Breast Cancer
  • Quality of Life
  • Taste Perception
  • Dysgeusia
  • Chemotherapy Effects
  • Nutritional Status
  • Sensory Testing

Interventions

OTHER

Taste Assessment / Nutritional Assessment / Quality of Life Assessment

Participants will undergo additional procedures as part of the study to assess taste function, nutritional status, and quality of life. These procedures include: * Taste assessment using standardized taste strips to measure recognition thresholds for the five basic tastes (sweet, sour, salty, bitter, umami) and chemesthetic sensitivity using strips impregnated with capsaicin. * Questionnaires to evaluate chemotherapy-induced taste alterations (CiTAS) and general quality of life (FACT-G). * Nutritional assessment, including evaluation of caloric and macronutrient intake using 24-hour dietary recalls, assessment of nutritional status according to GLIM criteria, and measurement of phase angle through bioelectrical impedance analysis (BIA). All procedures are non-invasive and performed in addition to the participants' standard chemotherapy treatment.

Sponsors & Collaborators

  • Azienda Sanitaria Locale CN2 Alba-Bra

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2027-12-31
Completion
2027-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07317752 on ClinicalTrials.gov