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Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics

NCT03031808 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2019-03-13

No results posted yet for this study

Summary

When a surgical procedure is performed under general anesthesia, the Airways are often secured With an endotracheal tube. Some patients experience sore throat thereafter. Studies have shown a reduction of these side effects when by use of muscle relaxants or a lidocain spray prior to the intubation. At Ostfold Hospital Trust, the investigators use one of the two methods or nothing. These methods will be studied systematically.

Heart rate and blood pressure rise during the intubation procedure. The investigators will also study the differences between the groups.

Conditions

  • Intubation Complication

Interventions

DRUG

Lidocaine spray (2%)

Spraying trachea from 2 cm above the vocal cords and 5 cm down with a straw with multiple side holes

DRUG

Muscle Relaxant (Rocuronium)

After induction of anesthesia, the participants are given 0,6 mg/kg bodyweight intravenously.

OTHER

No Muscle relaxant, no Lidocaine

This group get general anesthesia without Rocuronium or Lidocaine

Sponsors & Collaborators

  • Ostfold Hospital Trust

    lead OTHER

Principal Investigators

  • Jan Sverre Vamnes, MD, Ph.D. · Senior consultant

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-31
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03031808 on ClinicalTrials.gov