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Adjacent Segment Mechanics in Cervical Arthrodesis Patients

NCT03028402 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 106

Last updated 2025-02-06

No results posted yet for this study

Summary

This study aims to determine to what extent patient-specific factors, iatrogenic factors, and biomechanical factors influence cervical spine mechanics after single-level and two-level arthrodesis.

Conditions

  • Intervertebral Disc Degeneration

Interventions

PROCEDURE

C5-C6 arthrodesis

A standard Smith Robinson anterior medial approach to the cervical spine. Vertebral endplates will be prepared by removing the cartilage endplate. Tricortical anterior iliac crest autografts will be harvested with a low-speed oscillating saw. Allografts will be fresh-frozen, vacuum-sealed, nonradiated tricortical grafts. All grafts will be fashioned in a typical Smith-Robinson formation. The motion segment will be distracted approximately 2-mm beyond the graft height before the insertion of each graft. Fusion plate will be contoured to cervical lordosis. Cervical plates will be positioned using surgical midline markers. All rigid anterior plate fixations will be performed using titanium anterior fixed-angle screw systems.

Sponsors & Collaborators

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • William Anderst, PhD · University of Pittsburgh

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2024-12-30
Completion
2024-12-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03028402 on ClinicalTrials.gov