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Surgical Intervention of Spinal Arteriovenous Malformations and Fistulas

NCT03024749 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 380

Last updated 2017-06-06

No results posted yet for this study

Summary

Spinal arteriovenous fistulas (AVFs) and arteriovenous malformations (AVMs) are complex neurosurgical lesions that are very challenging to manage. Spinal vascular malformations account for 3%-4% of all intradural spinal cord mass lesions. Over the last few decades our understanding of these lesions has dramatically increased thanks to neuroimaging technology (e.g. spinal angiography and indocyanine green angiography). Various treatment modalities including conservative observation, endovascular embolization, microsurgical resection, radiation therapy, and combined therapies have been reported. The treatment for these AVMs and AVFs depends on their location, the type of malformation, the area of the spine involved, and the condition of the patient at the time of treatment. Due to the rarity of these spinal vascular lesions, reports of their management and outcomes have been limited to small series and case reports. And the rates of obliteration and outcomes are not satisfactory, especially the spinal AVMs. Spinal vascular lesions are rare but represent a formidable challenge for the treating neurosurgeon.The purpose of this study is to establish multimodality treatment mode and evaluate the anatomical cure rate and functional preservation rate.

Conditions

  • Spinal Cord Vascular Diseases

Sponsors & Collaborators

  • Beijing Tiantan Hospital

    collaborator OTHER

  • Beijing Tsinghua Chang Gung Hospital

    collaborator OTHER

  • Tianjin Medical University General Hospital

    collaborator OTHER

  • Peking University Third Hospital

    collaborator OTHER

  • Chinese PLA General Hospital

    collaborator OTHER

  • Beijing Hospital

    collaborator OTHER_GOV

  • General Hospital of Chinese Armed Police Forces

    collaborator OTHER

  • Beijing Haidian Hospital

    collaborator OTHER

  • China Rehabilitation Research Center

    collaborator OTHER_GOV

  • Hongqi Zhang, MD

    lead OTHER

Principal Investigators

  • Zhang Hongqi, MD · Neurosurgical Department, Xuanwu Hospital, Beijing

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-01
Primary Completion
2018-12-31
Completion
2019-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03024749 on ClinicalTrials.gov