The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study
NCT03010995 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2018-07-26
Summary
The goal of this project is to evaluate the nicotine induced acute cardiovascular changes in E-Cigarette users and also study the mechanism involved particularly with vascular impairment.
Conditions
- Cigarette Smoking Toxicity
- Nicotine
- Acute Cardiovascular Disease
Interventions
- DRUG
-
Prazosin
Prazosin will used to study the mechanism involved in nicotine induced acute cardiovascular changes
Sponsors & Collaborators
-
University of Louisville
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-03-13
- Primary Completion
- 2018-07-24
- Completion
- 2018-07-24
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Electronic Nicotine Delivery Devices and Potential Progression to Acute Lung Injury
NCT05316727 ·Status: COMPLETED
-
Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems
NCT05423340 ·Status: COMPLETED ·Phase: NA
-
Comparative Abuse Liability Among African American and White Smokers
NCT04646668 ·Status: COMPLETED ·Phase: NA
-
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH
NCT04449510 ·Status: COMPLETED ·Phase: NA
-
Vaporized Nicotine and Autonomic Control
NCT04613609 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products
NCT01964807 ·Status: COMPLETED ·Phase: NA
-
E-Cigarette and Cigarette Nicotine Delivery and Abuse Liability in Cigarette Smokers and Dual Users
NCT03943706 ·Status: WITHDRAWN
-
Clinical Pharmacology of Electronic Cigarettes
NCT02470754 ·Status: COMPLETED ·Phase: NA
-
Acute Health Effects of Short-term Use of E-cigarettes on Pulmonary and Cardiovascular System
NCT03742700 ·Status: COMPLETED ·Phase: NA
-
Switching to E-cigarettes in Smokers Not Interested in Quitting
NCT05703672 ·Status: RECRUITING ·Phase: PHASE3
-
Quit Smoking Study for People Who Use E-Cigarettes
NCT04946825 ·Status: COMPLETED ·Phase: PHASE2
-
The Influence of Electronic (ECIG) Heater Resistance on ECIG Acute Effects
NCT03496116 ·Status: COMPLETED ·Phase: NA
-
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
NCT03839745 ·Status: COMPLETED ·Phase: NA
-
The Effects of Electronic Cigarette Smoking on the Arterial Wall and Endothelial Glycocalyx Properties of Smokers
NCT03039920 ·Status: UNKNOWN ·Phase: NA
-
Acute Cardiorespiratory Effects of E-cigarette Inhalation
NCT02899234 ·Status: COMPLETED ·Phase: NA
-
E-Cigarette Aerosol, Conventional Cigarette Smoke, and Myocardial Perfusion
NCT02612701 ·Status: TERMINATED ·Phase: NA
-
The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products
NCT03492463 ·Status: COMPLETED ·Phase: PHASE2
-
Responses to Regulated E-Cigarette Advertisements
NCT05207033 ·Status: COMPLETED ·Phase: NA
-
Nicotine Pharmacokinetic in Blood and Analysis of Exhaled Breath After E-cigarette Smoking.
NCT03573154 ·Status: UNKNOWN ·Phase: NA
-
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
NCT06077240 ·Status: RECRUITING ·Phase: NA
-
Vaping and Smoking Withdrawal Project
NCT05772845 ·Status: RECRUITING ·Phase: NA
-
Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes
NCT05706701 ·Status: COMPLETED ·Phase: NA
-
Developing Evidence to Inform Regulatory Policy on Nicotine Content in E-Liquids
NCT06619964 ·Status: ENROLLING_BY_INVITATION
-
e-Cigarette - DNA Adducts
NCT03284632 ·Status: COMPLETED
-
Monitoring the Transition From Smoking to E-cigarettes
NCT02752022 ·Status: UNKNOWN