To Observe the Efficacy and Safety by Comparing Chemotherapy(Docetaxel, Oxaliplatin Plus S1 ) Followed With Radical Resection Versus Chemotherapy Alone in Advanced Gastric Cancer With Single Non-curable Factor.
NCT03001726 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 228
Last updated 2022-05-06
Summary
Investigators assessed the effectiveness of conversional gastrectomy compared with chemotherapy alone following docetaxel, oxalipaltin and S1 therapy for advanced gastric cancer with a single non-curable factor.
Conditions
Interventions
- PROCEDURE
-
Gastrectomy
In patients assigned to surgery followed by chemo- therapy, a total, distal, or proximal gastrectomy with metastasis dissection was done depending on tumour location.
- DRUG
-
oxaliplatin 100 mg/m2
- DRUG
-
S1
S1 40mg/m2
- DRUG
-
docetaxel 40 mg/m2
Sponsors & Collaborators
-
Shanghai Zhongshan Hospital
lead OTHER
Principal Investigators
-
Tianshu Liu, Physician · Zhongshan Hopital
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-31
- Primary Completion
- 2022-06-30
- Completion
- 2023-12-31
Countries
- China
Study Locations
More Related Trials
-
Adjuvant Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer
NCT02867839 ·Status: TERMINATED ·Phase: PHASE3
-
Docetaxel + Oxaliplatin + S-1 in Potentially Operable Gastric or Gastroesophageal Adenocarcinoma
NCT00816543 ·Status: COMPLETED ·Phase: PHASE2
-
The Efficacy of Oxaliplatin Plus S-1 for Treatment of Gastric Cancer
NCT01531452 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel+Oxaliplatin+S-1 (DOS) Regimen as Neoadjuvant Chemotherapy in Advanced Gastric Cancer
NCT01515748 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of S-1 Plus Oxaliplatin in First-line Treatment of Ederly Patients With Advanced Gastric Cancer
NCT04694404 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Intraperitoneal Paclitaxel in Combination With SOX Compared With SOX Alone in Gastric Cancer With Malignant Ascites
NCT03475615 ·Status: UNKNOWN ·Phase: PHASE3
-
Compare S-1 Plus Oxaliplatin to S-1 as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer
NCT01795027 ·Status: UNKNOWN ·Phase: PHASE3
-
Duration of Adjuvant Chemotherapy for Gastric Cancer Patients at Pathological N3 Stage
NCT06194981 ·Status: RECRUITING
-
S-1 Combined Cisplatin HIPEC for Palliative Operation Gastric Cancer of Stage IV Limited Peritoneal Metastasis
NCT02291211 ·Status: UNKNOWN ·Phase: PHASE2
-
Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction Cancer
NCT01747707 ·Status: UNKNOWN ·Phase: PHASE2
-
Peri-operative Chemotherapy With ECX or XP in the Treatment of Advanced Gastric Cancer
NCT01558947 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy Alone Versus Surgery Plus Chemotherapy for Distal Gastric Cancer With One Non-curable Factor
NCT03399253 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
S-1 Plus Oxaliplatin Compared With Fluorouracil, Leucovorin Calcium Plus Oxaliplatin as Perioperative Chemotherapy for Advanced Gastric Carcinoma
NCT01364376 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Perioperative Chemotherapy Plus PD-1 Antibody in Gastric Cancer
NCT04367025 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of S-1 and Oxaliplatin as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer
NCT01090505 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase III Study to Compare Perioperative Chemotherapy of Oxaliplatin Combined With S-1(SOX) Versus SOX or Oxaliplatin With Capecitabine (XELOX) as Post-operative Chemotherapy in Locally Advanced Gastric Adenocarcinoma With D2 Dissection
NCT01534546 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy of Perioperative Chemotherapy Plus PD-1 Antibody in the Locally Advanced Gastric Cancer
NCT04250948 ·Status: UNKNOWN ·Phase: PHASE2
-
Docetaxel and S-1 Combination Therapy as Second-line Treatment for Advanced Gastric Cancer
NCT03137004 ·Status: UNKNOWN ·Phase: PHASE2
-
Randomized Multicenter Study Comparing Docetaxel Plus Cisplatin and 5-FU to Cisplatin Plus 5-FU in Advanced Gastric Cancer
NCT00290966 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Docetaxel Versus Docetaxel Plus Cisplatin Versus Docetaxel Plus S-1 as Second-line Chemotherapy in Metastatic Gastric Cancer
NCT00980603 ·Status: UNKNOWN ·Phase: PHASE2
-
Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC
NCT04890392 ·Status: UNKNOWN ·Phase: PHASE2
-
Nab-paclitaxel Combined With Oxaliplatin and S-1 for Perioperative Treatment of Advanced Gastric Cancer
NCT05052931 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficiency of XELOX Neoadjuvant Chemotherapy in Gastric Cancer
NCT01665274 ·Status: TERMINATED ·Phase: PHASE2
-
Receiving Modified Chemotherapy Followed With Radical Resection After Neoadjuvant Chemotherapy
NCT03322969 ·Status: UNKNOWN ·Phase: PHASE2
-
Laparoscopic D2 Distal Gastrectomy Following Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancers
NCT03468712 ·Status: UNKNOWN ·Phase: NA