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Pulmonary Vascular Disease Phenomics Program PVDOMICS

NCT02980887 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1195

Last updated 2025-11-17

No results posted yet for this study

Summary

It is recognized that patients with various forms of heart and lung disease exhibit varying degrees of pulmonary hypertension, pulmonary vascular remodeling, and right ventricular dysfunction. The genetic, molecular, and cellular processes driving these phenomena are not well understood. Rapid advances in high throughput omic methodology, combined with powerful bioinformatics and network biology capability, have created the opportunity to conduct studies that broadly search for homologies and differences across the spectrum of disease states associated with pulmonary hypertension, and determinants of the spectrum of right ventricular compensation that accompanies these conditions

Conditions

Interventions

OTHER

No Intervention

There is no intervention in this observational study

Sponsors & Collaborators

  • Brigham and Women's Hospital

    collaborator OTHER

  • Columbia University

    collaborator OTHER

  • Weill Medical College of Cornell University

    collaborator OTHER

  • Johns Hopkins University

    collaborator OTHER

  • Mayo Clinic

    collaborator OTHER

  • University of Arizona

    collaborator OTHER

  • Vanderbilt University

    collaborator OTHER

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Nicholas S Hill, MD · Tufts University Medical Center

  • Lei Xiao, MD · National Heart, Lung, and Blood Institute (NHLBI)

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-30
Primary Completion
2029-12-31
Completion
2029-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02980887 on ClinicalTrials.gov