Characterization of Epicardial and Pericardial Adipose Tissue in Coronary Artery Disease

NCT02965625 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2020-11-27

No results posted yet for this study

Summary

Human epicardial fat is the true visceral fat depot of the heart, and its regional distribution and physiology is of growing scientific and clinical interest. This study aims to characterize the expression profile and function of the epicardial and pericardial adipose tissue compartments of the heart (EAT and PAT). EAT and PAT adipose biopsies will be obtained from patients undergoing coronary artery bypass graft surgery (CABG) or valve replacement surgery.

Conditions

Sponsors & Collaborators

  • Copenhagen University Hospital, Denmark

    collaborator OTHER
  • University of Copenhagen

    collaborator OTHER
  • The Novo Nordisk Foundation Center for Basic Metabolic Research

    collaborator OTHER
  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Regitse H Christensen, MD · Rigshospitalet, Denmark

  • Sarah E Heywood, PhD · Rigshospitalet, Denmark

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-31
Primary Completion
2018-06-30
Completion
2018-06-30

Countries

  • Denmark

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02965625 on ClinicalTrials.gov