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Junctional AV Ablation in CRT-D: JAVA-CRT

NCT02946853 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2022-01-25

Study results available
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Summary

Cardiac resynchronization therapy (CRT) is a demonstrably effective device intervention for patients with heart failure with reduced ejection fraction and specific indication. However, many patients with heart failure (HF) are unable to maintain sinus rhythm and approximately 30-36% of CRT patients are in atrial fibrillation (AF).

Conditions

  • Systolic Heart Failure
  • Atrial Fibrillation (Permanent)

Interventions

PROCEDURE

Atrioventricular junctional (AVJ) ablation

RF energy delivery to AV node to create complete AV block

DEVICE

Cardiac resynchronization therapy - defibrillator

Insertion of device capable of providing biventricular pacing and cardiac defibrillation

Sponsors & Collaborators

  • University of Rochester

    lead OTHER

Principal Investigators

  • Jonathan S Steinberg, MD · University of Rochester

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-01
Primary Completion
2020-08-31
Completion
2020-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02946853 on ClinicalTrials.gov