Light Therapy in Cardiopulmonary Bypass Surgery
NCT02928887 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2022-01-20
Summary
The goal of this study is to determine whether or not exposure to blue spectrum light reduces acute kidney injury and systemic inflammation in subjects undergoing cardiopulmonary bypass. Subjects scheduled to undergo cardiopulmonary bypass surgery will be exposed to either bright (1000 lux) blue spectrum (480nm) light or to ambient, white fluorescent light for a 24 hour photoperiod the day prior to surgery and for a 24 hour photoperiod in the immediate postoperative period.
Conditions
Interventions
- OTHER
-
Blue light
Exposure to high illuminance (1000 lux), blue spectrum (480 nm) light for a 24-hour photoperiod immediately before surgery and a 24-hour photoperiod immediately after surgery
Sponsors & Collaborators
-
University of Pittsburgh
lead OTHER
Principal Investigators
-
Matthew R Rosengart, MD MPH · University of Pittsburgh
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-09-01
- Primary Completion
- 2022-01-19
- Completion
- 2022-06-30
Countries
- United States
Study Locations
More Related Trials
-
Management of Bleeding Following Cardiopulmonary Bypass
NCT00672516 ·Status: COMPLETED
-
Cardiopulmonary Bypass and Inflammatory Response
NCT00167349 ·Status: COMPLETED
-
Methylene Blue-Enhanced Ultrafiltration Improves Outcomes After Cardiopulmonary Bypass
NCT07212842 ·Status: COMPLETED ·Phase: PHASE2
-
Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.
NCT01802619 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Clinical Outcomes Between Pulsatile and Non-Pulsatile Flow During Cardiopulmonary Bypass
NCT07009730 ·Status: COMPLETED
-
Lung Perfusion With Oxygenated Blood During Aortic Clamping
NCT01186510 ·Status: COMPLETED ·Phase: NA
-
Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery
NCT02981680 ·Status: COMPLETED ·Phase: NA
-
Effect of Remote Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery
NCT00889811 ·Status: COMPLETED ·Phase: PHASE1
-
Cardiopulmonary Bypass (CPB) Pumps and Blood Activation
NCT00187967 ·Status: UNKNOWN ·Phase: NA
-
Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)
NCT04296071 ·Status: RECRUITING
-
Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery
NCT01098409 ·Status: UNKNOWN ·Phase: PHASE2
-
Tissue Oxygenation During Heart Surgery
NCT01347827 ·Status: COMPLETED
-
Ultrasound to Prevent Leg Wound Complications in Heart Bypass.
NCT02307084 ·Status: TERMINATED ·Phase: NA
-
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function
NCT01469676 ·Status: COMPLETED ·Phase: NA
-
Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery
NCT03376542 ·Status: COMPLETED ·Phase: NA
-
Quantification of Thrombocytes Number and Function in Patients Undergoing Prolonged Extracorporeal Circulation
NCT02771223 ·Status: UNKNOWN
-
Plasma Angiopoietin Levels in Children Following Cardiopulmonary Bypass
NCT01489475 ·Status: COMPLETED
-
Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass
NCT02979158 ·Status: COMPLETED ·Phase: NA
-
Predictors Of Outcome After Coronary Artery Bypass Graft Surgery Using Cardiopulmonary Bypass
NCT07034716 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Nitric Oxide During Cardiopulmonary Bypass in Adult Surgery
NCT04807413 ·Status: UNKNOWN ·Phase: PHASE3
-
One-lung Ventilation During Internal Thoracic Artery Grafting in Cardiac Surgery
NCT02823054 ·Status: UNKNOWN ·Phase: NA
-
CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)
NCT00107666 ·Status: TERMINATED ·Phase: PHASE2
-
Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass
NCT00131040 ·Status: COMPLETED ·Phase: NA
-
Effect of Parathyroidectomy on Cardiovascular Health
NCT02989428 ·Status: COMPLETED ·Phase: NA
-
Intermittent Normoxia Reduces Myocardial Reperfusion Injury
NCT01348906 ·Status: UNKNOWN ·Phase: NA